Frontotemporal Lobar Degeneration

Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.

Also Known As:

Degeneration, Frontotemporal Lobar; FTLD; Degenerations, Frontotemporal Lobar; FTLDs; Frontotemporal Lobar Degenerations; Lobar Degeneration, Frontotemporal; Lobar Degenerations, Frontotemporal

Nervous System Diseases: 14178
- Neurodegenerative Diseases: 42472
  - TDP-43 Proteinopathies: 211
    - Frontotemporal Lobar Degeneration: 1673
- Central Nervous System Diseases: 4213
  - Brain Diseases: 15694
    - Dementia: 38184
      - Frontotemporal Lobar Degeneration: 1673
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Proteostasis Deficiencies: 1400
    - TDP-43 Proteinopathies: 211
      - Frontotemporal Lobar Degeneration: 1673
Mental Disorders: 24177
- Neurocognitive Disorders: 1448
  - Dementia: 38184
    - Frontotemporal Lobar Degeneration: 1673

Marleen Van Den Broeck Selected Research

Marleen Van Den Broeck Research Topics

Disease

Drug/Important Bio-Agent (IBA)